Delving into the Tumour Microenvironment to Improve Understanding of the Immunosuppressive Environment to Increase Effectivity of Neoantigen Therapies
Time: 12:05 pm
day: Pre-Conference Day
Details:
Due to the great heterogeneity of tumours, they can evolve capabilities to allow them to escape and evade the immune system. Moreover, the tumour microenvironment may have compounds or signals which block interactions between therapies and the tumour. Therefore, in order to create the most effective and immunogenic therapies, these mechanisms need to be understood further to enable adaptation to the tumour and its microenvironment.
- Navigating the compounds in the tumour microenvironment which help it overcome the immune system.
- Analyzing the presence of microbial species which can impact the efficacy of the therapies.
- Improving awareness of tumour microenvironment to reduce failures.
- How to overcome the challenge of tumour immune escape by targeting multiple neoantigens?
- How to design vaccines and therapeutics to face challenges of tumour immune escape?
- Are there additional signals to identify to ensure success of the therapies?
