Olivier Lantz

Company: Institut Curie

Job title: Head of the Hospital Clinical Immunology Laboratory, Group Leader

Seminars:

Fireside Chat: Creating Alignment in Immune Monitoring & Interpretation of Read Outs to Increase Investment Opportunities & Accurately Measure Clinical Efficacy 4:00 pm

Creating a robust, methodical protocol for monitoring and analysing immune response to enable investors to contextualise and compare therapeutic efficacy Ensuring appropriate read outs and biomarkers are selected for immune monitoring to accurately evaluate immunogenicity of neoantigen vaccines and cell therapies Determining a desired level of de novo and secondary immune response to quantify efficacyRead more

day: Day Two

From the Discovery & Validation of Public Tumour-Specific Neoantigen Derived From the Dark Genome to a Clinical Trial in Uveal Melanoma: An Academic Perspective 2:45 pm

How to test immunogenicity: in healthy donors, in patients or in preclinical models? What level of preclinical validation? Refining early phase testing: vaccine alone or in association with immunomodulators? Which one? Which schedule? Discussing primary objectives: CD4 and CD8 responses instead of clinical response. Which methods? How to monitor the Treg response?Read more

day: Day One